IL-21 anticorps (C-Term)

N° du produit ABIN2788558

Détail du produit anti-IL-21 anticorps

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Épitope: C-Term

Reactivité: Humain, Boeuf (Vache), Cheval, Porc, Chien, Chévre, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-21 est non-conjugé

Application: Western Blotting (WB)

Séquence: ERIINVSIKK LKRKPPSTNA GRRQKHRLTC PSCDSYEKKP PKEFLERFKS

Homologie: Cow: 79%, Dog: 86%, Goat: 86%, Horse: 79%, Human: 100%, Pig: 86%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against IL21. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL21

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL-21

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Autre désignation: IL21 (IL21 Produits)

Synonymes: anticorps IL-21, anticorps Za11, anticorps interleukin 21, anticorps IL21, anticorps Il21

Sujet: This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: IL-21, Za11
Protein Interaction Partner: FBXO25, IL21R, DGKA,
Protein Size: 153

Poids moléculaire: 16 kDa

ID gène: 59067

NCBI Accession: NM_001207006, NP_001193935

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response