CYB5R3 anticorps (C-Term)
Aperçu rapide pour CYB5R3 anticorps (C-Term) (ABIN2788600)
Antigène
Voir toutes CYB5R3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- IRAIMKDPDD HTVCHLLFAN QTEKDILLRP ELEELRNKHS ARFKLWYTLD
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against CYB5R3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CYB5R3
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 301 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))
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Autre désignation
- CYB5R3
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Sujet
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This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.
Alias Symbols: B5R, DIA1
Protein Interaction Partner: SUMO2, PARK2, UBC, SLC1A5, SDHA, RPS7, HSPA1L, CDK2, SPP1, CYB5R3, CYB5A, HBG2, CYCS, ESR1,
Protein Size: 301 -
Poids moléculaire
- 34 kDa
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ID gène
- 1727
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NCBI Accession
- NM_000398, NP_000389
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UniProt
- P00387
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Pathways
- SARS-CoV-2 Protein Interactome
Antigène
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