Actin anticorps (C-Term)

N° du produit ABIN2788635

Détail du produit anti-Actin anticorps

Antigène: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Chien, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Actin est non-conjugé

Application: Western Blotting (WB)

Séquence: STMKIKIIAP PERKYSVWIG GSILASLSTF QQMWITKQEY DEAGPSIVHR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ACTA1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 377 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Actin

Antigène: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Autre désignation: ACTA1 (ACTA1 Produits)

Synonymes: anticorps ACTA, anticorps ASMA, anticorps CFTD, anticorps CFTD1, anticorps CFTDM, anticorps MPFD, anticorps NEM1, anticorps NEM2, anticorps NEM3, anticorps acta, anticorps asma, anticorps cftd, anticorps cftd1, anticorps cftdm, anticorps mpfd, anticorps nem1, anticorps AA959943, anticorps Acta-2, anticorps Acts, anticorps Actsk-1, anticorps actc, anticorps actc1, anticorps cfk, anticorps hm:zeh0631, anticorps zeh0631, anticorps acta1, anticorps hm:zeh0293, anticorps zgc:112098, anticorps actin, alpha 1, skeletal muscle, anticorps actin, alpha 1, skeletal muscle L homeolog, anticorps actin, alpha 1b, skeletal muscle, anticorps actin, muscle, anticorps actin, alpha skeletal muscle, anticorps actin, alpha 1a, skeletal muscle, anticorps ACTA1, anticorps acta1.L, anticorps acta1, anticorps Acta1, anticorps acta1b, anticorps LOC100533357, anticorps LOC109479779, anticorps LOC109108280, anticorps acta1a

Sujet: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Alias Symbols: ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3
Protein Interaction Partner: ABL1, TRIM63, TRIM55, CEP57, AMOT, UBC, SUMO3, CDKN2A, ACTG1, BRK1, ACTBL2, NCKAP1, LRCH3, MAPK14, DSTN, NMI, UBL4A, ABRA, ABLIM2, POLR1B, RRN3, HTRA2, PTPN22, ABLIM3, BTK, CCT2, TRAF3IP1, TCP1, SNCA, PARK2, LGALS3, SHC1, GSN, CDK2, CUL1, ISG15, YWHAZ, RE
Protein Size: 377

Poids moléculaire: 42 kDa

ID gène: 58

NCBI Accession: NM_001100, NP_001091

UniProt: P68133

Pathways: Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development