Actin anticorps (C-Term)

N° du produit ABIN658563

Détail du produit anti-Actin anticorps

Antigène: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Épitope: AA 346-375, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Actin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Specificité: This ACTA1/?-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-376 amino acids from the C-terminal region of human ACTA1/?-actin.

Homologie: Cow (Bovine),Chicken,Mouse (Murine),Pig (Porcine),Rat (Rattus),Rabbit,Xenopus laevis

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 AA from the C-terminal region of human ACTA1/Alpha-actin.

Clone: RB35391

Isotype: Ig Fraction

Information d'application

Indications d'application: WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-Actin (ABIN658563)

Xiao, Gao, Gao, Zhao, Hong, Li, Yao, Cheng, Zhou: "Directed Differentiation of Zebrafish Pluripotent Embryonic Cells to Functional Cardiomyocytes." dans: Stem cell reports, Vol. 7, Issue 3, pp. 370-382, (2017) (PubMed).

Ying, Xie, Bai, Chen, Wang, Zhang, Morishita, Sun, Rajagopalan: "Exposure to concentrated ambient particulate matter induces reversible increase of heart weight in spontaneously hypertensive rats." dans: Particle and fibre toxicology, Vol. 12, Issue 1, pp. 15, (2015) (PubMed).

Détails sur Actin

Antigène: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Abstract: ACTA1 Produits

Synonymes: anticorps ACTA, anticorps ASMA, anticorps CFTD, anticorps CFTD1, anticorps CFTDM, anticorps MPFD, anticorps NEM1, anticorps NEM2, anticorps NEM3, anticorps acta, anticorps asma, anticorps cftd, anticorps cftd1, anticorps cftdm, anticorps mpfd, anticorps nem1, anticorps AA959943, anticorps Acta-2, anticorps Acts, anticorps Actsk-1, anticorps actc, anticorps actc1, anticorps cfk, anticorps hm:zeh0631, anticorps zeh0631, anticorps acta1, anticorps hm:zeh0293, anticorps zgc:112098, anticorps actin, alpha 1, skeletal muscle, anticorps actin, alpha 1, skeletal muscle L homeolog, anticorps actin, alpha 1b, skeletal muscle, anticorps actin, muscle, anticorps actin, alpha skeletal muscle, anticorps actin, alpha 1a, skeletal muscle, anticorps ACTA1, anticorps acta1.L, anticorps acta1, anticorps Acta1, anticorps acta1b, anticorps LOC100533357, anticorps LOC109479779, anticorps LOC109108280, anticorps acta1a

Sujet: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Synonyms: Actin, alpha skeletal muscle,ACTA1,ACTA

Poids moléculaire: 42051 Da

ID gène: 58

UniProt: P68133

Pathways: Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development