FLT1 anticorps (C-Term)

N° du produit ABIN2788655

Cet anticorps anti-FLT1 est un anticorps Lapin Polyclonal détectant FLT1 dans WB. Adapté pour Humain, Rat, Lapin, Chien, Cobaye, Cheval, Boeuf (Vache) et Chévre.

Aperçu rapide pour FLT1 anticorps (C-Term) (ABIN2788655)

Antigène: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Reactivité: Humain, Rat, Lapin, Chien, Cobaye, Cheval, Boeuf (Vache), Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FLT1 anticorps

Épitope: C-Term

Séquence: DLRVTSKSKE SGLSDVSRPS FCHSSCGHVS EGKRRFTYDH AELERKIACC

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 77%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FLT1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FLT1

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FLT1

Antigène: FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

Autre désignation: FLT1

Sujet: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Protein Interaction Partner: SRPK1, VEGFA, Nedd4, UBC, ATR, NRP2, NRP1, VEGFB, PTK2B, PGF, PTK2, SHC1, NCK1, PLCG2, KDR, PTPN11, PLCG1, FLT1, YES1, CRK, FYN, CTNNB1, GRB2, SHC2, PIK3R1,
Protein Size: 463

Poids moléculaire: 50 kDa

ID gène: 2321

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals