LHCGR anticorps (C-Term)
Aperçu rapide pour LHCGR anticorps (C-Term) (ABIN2788657)
Antigène
Voir toutes LHCGR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- LHCGR Antibody - C-terminal region
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Séquence
- LLLSKFGCCK RRAELYRRKD FSAYTSNCKN GFTGSNKPSQ STLKLSTLHC
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Homologie
- Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against LHCGR. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human LHCGR
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61025-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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Autre désignation
- LHCGR
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Sujet
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Background Information: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.
Gene Name: luteinizing hormone/choriogonadotropin receptor
Alternative Symbols: HHG, LHR, LCGR, LGR2, ULG5, LHRHR, LSH-R, LH/CGR, LH/CG-R
Protein Name: lutropin-choriogonadotropic hormone receptor
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Poids moléculaire
- 69kDa
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ID gène
- 3973
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UniProt
- P22888
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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