Topoisomerase I anticorps (N-Term)

N° du produit ABIN2788658

Cet anticorps anti-Topoisomerase I est un anticorps Lapin Polyclonal détectant Topoisomerase I dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin et Chien.

Aperçu rapide pour Topoisomerase I anticorps (N-Term) (ABIN2788658)

Antigène: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Topoisomerase I est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Topoisomerase I anticorps

Épitope: N-Term

Séquence: SNSEHKDSEK KHKEKEKTKH KDGSSEKHKD KHKDRDKEKR KEEKVRASGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TOP1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 765 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Topoisomerase I

Antigène: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Autre désignation: TOP1

Sujet: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Alias Symbols: TOPI
Protein Interaction Partner: SUMO2, SUMO3, MDM2, UBC, SUMO1, ERG, RNF2, EED, SHFM1, CDK14, TARDBP, CDK2, HDAC9, EIF2AK2, PARP1, WHSC1, VCAM1, ITGA4, IL7R, VCP, PA2G4, NKX3-1, ESR1, RBM39, APP, UTP20, NCSTN, SUPT16H, RBM14, SF3B6, SRSF11, TPR, SNRPD1, S100A9, RPS14, HNRNPM, IK, HNRNPC
Protein Size: 765

Poids moléculaire: 91 kDa

ID gène: 7150

NCBI Accession: NM_003286, NP_003277

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance