Topoisomerase I anticorps (N-Term)

N° du produit ABIN2788658

Détail du produit anti-Topoisomerase I anticorps

Antigène: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Topoisomerase I est non-conjugé

Application: Western Blotting (WB)

Séquence: SNSEHKDSEK KHKEKEKTKH KDGSSEKHKD KHKDRDKEKR KEEKVRASGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TOP1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 765 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Topoisomerase I

Antigène: Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

Autre désignation: TOP1 (TOP1 Produits)

Synonymes: anticorps CG6146, anticorps Dmel\\CG6146, anticorps TOP1, anticorps TopI, anticorps Topo I, anticorps TopoI, anticorps dTopoI, anticorps l(1)G0134, anticorps l(1)G0201, anticorps l(1)G0229, anticorps l(1)G0278, anticorps l(1)top1, anticorps top1, anticorps topo I, anticorps topoI, anticorps DNA topoisomerase 1 beta, anticorps DNA topoisomerase I alpha, anticorps MGO1, anticorps MGOUN 1, anticorps MTE17.1, anticorps MTE17_1, anticorps TOP1BETA, anticorps TOPOISOMERASE 1, anticorps TOPI, anticorps AI467334, anticorps D130064I21Rik, anticorps Top-1, anticorps Ab2-086, anticorps topi, anticorps Topoisomerase 1, anticorps DNA topoisomerase I, anticorps DNA topoisomerase I alpha, anticorps DNA topoisomerase 1, anticorps topoisomerase (DNA) I, anticorps DNA topoisomerase I, gene 1 L homeolog, anticorps Top1, anticorps top1, anticorps topA, anticorps ZMO1193, anticorps MRAD2831_RS63095, anticorps Lferr_0016, anticorps PC1_2015, anticorps Za10_0136, anticorps Gbro_0575, anticorps Dd586_2108, anticorps Kvar_3044, anticorps Alvin_2069, anticorps Dacet_0849, anticorps Mrub_1615, anticorps Arnit_2962, anticorps Ndas_4953, anticorps Trad_2377, anticorps Acear_1653, anticorps Mahau_0844, anticorps Mesop_4109, anticorps Thein_1586, anticorps Theth_0241, anticorps TOP1ALPHA, anticorps top-1, anticorps TOP1, anticorps top1.1.L

Classe de substances: Viral Protein

Sujet: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Alias Symbols: TOPI
Protein Interaction Partner: SUMO2, SUMO3, MDM2, UBC, SUMO1, ERG, RNF2, EED, SHFM1, CDK14, TARDBP, CDK2, HDAC9, EIF2AK2, PARP1, WHSC1, VCAM1, ITGA4, IL7R, VCP, PA2G4, NKX3-1, ESR1, RBM39, APP, UTP20, NCSTN, SUPT16H, RBM14, SF3B6, SRSF11, TPR, SNRPD1, S100A9, RPS14, HNRNPM, IK, HNRNPC
Protein Size: 765

Poids moléculaire: 91 kDa

ID gène: 7150

NCBI Accession: NM_003286, NP_003277

UniProt: P11387

Pathways: Caspase Cascade in Apoptosis, Stem Cell Maintenance