BID anticorps (C-Term)

N° du produit ABIN2788659

Cet anticorps Lapin Polyclonal détecte spécifiquement BID dans WB et IF. Il présente une réactivité envers Humain, Chien et Cheval.

Aperçu rapide pour BID anticorps (C-Term) (ABIN2788659)

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Reactivité: Humain, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BID est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-BID anticorps

Épitope: C-Term

Séquence: LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH

Homologie: Dog: 86%, Horse: 86%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BID. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 241 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BID

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Autre désignation: BID

Sujet: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alias Symbols: FP497, MGC15319, MGC42355
Protein Interaction Partner: AHCYL1, REL, MCL1, BCL2, BCL2L1, GZMB, CASP3, BAG3, CAV1, SQSTM1, VCP, UBQLN2, RPA2, RPA1, UBC, TUBB2B, FBN3, RBM48, CRNKL1, ZHX1, C14orf1, SETDB1, PLEKHM1, TLE1, GBP2, GAPDH, CRMP1, ITCH, BID, BCL2L2, CASP8, CASP10, YWHAB, BCL2A1, CSNK1E, CASP2, BAK1, CS
Protein Size: 241

Poids moléculaire: 27 kDa

ID gène: 637

NCBI Accession: NM_197966, NP_932070

UniProt: B3KT21

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity