BID anticorps (C-Term)
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- Antigène Voir toutes BID Anticorps
- BID (BH3 Interacting Domain Death Agonist (BID))
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Épitope
- C-Term
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Reactivité
- Humain, Chien, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BID est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Séquence
- LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH
- Homologie
- Dog: 86%, Horse: 86%, Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against BID. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product BID Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 241 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- BID (BH3 Interacting Domain Death Agonist (BID))
- Autre désignation
- BID (BID Produits)
- Synonymes
- anticorps FP497, anticorps 2700049M22Rik, anticorps AI875481, anticorps AU022477, anticorps BID, anticorps bid, anticorps si:ch211-238n5.6, anticorps fp497, anticorps xbid, anticorps DKFZp469E066, anticorps BH3 interacting domain death agonist, anticorps BH3 interacting domain death agonist S homeolog, anticorps BID, anticorps Bid, anticorps bida, anticorps bid.S, anticorps bid
- Sujet
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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alias Symbols: FP497, MGC15319, MGC42355
Protein Interaction Partner: AHCYL1, REL, MCL1, BCL2, BCL2L1, GZMB, CASP3, BAG3, CAV1, SQSTM1, VCP, UBQLN2, RPA2, RPA1, UBC, TUBB2B, FBN3, RBM48, CRNKL1, ZHX1, C14orf1, SETDB1, PLEKHM1, TLE1, GBP2, GAPDH, CRMP1, ITCH, BID, BCL2L2, CASP8, CASP10, YWHAB, BCL2A1, CSNK1E, CASP2, BAK1, CS
Protein Size: 241 - Poids moléculaire
- 27 kDa
- ID gène
- 637
- NCBI Accession
- NM_197966, NP_932070
- UniProt
- B3KT21
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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