BID anticorps (C-Term)

N° du produit ABIN2788659

Cet anticorps Lapin Polyclonal détecte spécifiquement BID dans WB et IF. Il présente une réactivité avec des échantillons de Humain, Rat, Chien et Cheval.

Aperçu rapide pour BID anticorps (C-Term) (ABIN2788659)

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Reactivité: Humain, Rat, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BID est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-BID anticorps

Épitope: C-Term

Fonction: BID Antibody - C-terminal region

Séquence: LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH

Homologie: Dog: 86%, Horse: 86%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BID. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61037-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur BID

Antigène: BID (BH3 Interacting Domain Death Agonist (BID))

Autre désignation: BID

Sujet:

Background Information: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Gene Name: BH3 interacting domain death agonist

Alternative Symbols: FP497

Protein Name: cDNA FLJ37476 fis, clone BRAWH2012827, highly similar to Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 1, mRNA EMBL BAG52933.1

Poids moléculaire: 27kDa

ID gène: 637

NCBI Accession: NP_932070

UniProt: B3KT21

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity