Hexokinase 1 anticorps (N-Term)

N° du produit ABIN2788663

Cet anticorps anti-Hexokinase 1 est un anticorps Lapin Polyclonal détectant Hexokinase 1 dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Lapin, Poisson zèbre (Danio rerio), Cheval et Cobaye.

Aperçu rapide pour Hexokinase 1 anticorps (N-Term) (ABIN2788663)

Antigène: Hexokinase 1 (HK1)

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexokinase 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Hexokinase 1 anticorps

Épitope: N-Term

Séquence: CQQSKIDEAI LITWTKRFKA SGVEGADVVK LLNKAIKKRG DYDANIVAVV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against HK1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 921 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Hexokinase 1

Antigène: Hexokinase 1 (HK1)

Autre désignation: HK1

Sujet: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alias Symbols: HK1-ta, HK1-tb, HK1-tc, HKI, HXK1
Protein Interaction Partner: SUMO2, SUMO3, STAU1, UBC, EGFR, SUMO1, NEDD8, MDM2, WDR61, UBA5, PARP6, NSFL1C, ARFGAP1, UBXN1, TWF2, FKBP9, PDCD10, PROSC, PLAA, GTF3C4, TUFM, TUBB2A, SGTA, RARS, PCNA, HEXB, HEXA, CAPN2, ASL, AHCY, PARK2, ATF2, VDAC1, LIG4, APP, AKT1, CDK2, SIRT7, ICT1,
Protein Size: 921

Poids moléculaire: 103 kDa

ID gène: 3098

NCBI Accession: NM_033498, NP_277033

UniProt: P19367

Pathways: Carbohydrate Homeostasis, L'effet Warburg