CD13 anticorps (N-Term)

N° du produit ABIN2788665

L’anticorps Lapin Polyclonal anti-CD13 a été validé pour WB. Il convient pour détecter CD13 dans des échantillons de Humain, Rat, Cheval, Cobaye, Chien et Lapin.

Aperçu rapide pour CD13 anticorps (N-Term) (ABIN2788665)

Antigène: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Reactivité: Humain, Rat, Cheval, Cobaye, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD13 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD13 anticorps

Épitope: N-Term

Séquence: VGGSQPPDID KTELVEPTEY LVVHLKGSLV KDSQYEMDSE FEGELADDLA

Homologie: Dog: 79%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Rabbit: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ANPEP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ANPEP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 967 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD13

Antigène: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Autre désignation: ANPEP

Sujet: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Alias Symbols: APN, CD13, GP150, LAP1, P150, PEPN
Protein Interaction Partner: UBC, ANPEP, Cep76, TM4SF1,
Protein Size: 967

Poids moléculaire: 106 kDa

ID gène: 290

NCBI Accession: NM_001150, NP_001141

UniProt: P15144

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones