Hexosaminidase A anticorps (C-Term)

N° du produit ABIN2788673

Cet anticorps anti-Hexosaminidase A Polyclonal Lapin (ABIN2788673) détecte spécifiquement Hexosaminidase A dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cobaye, Porc, Boeuf (Vache), Cheval, Lapin et Mouton.

Aperçu rapide pour Hexosaminidase A anticorps (C-Term) (ABIN2788673)

Antigène: Hexosaminidase A (HEXA)

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Porc, Boeuf (Vache), Cheval, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexosaminidase A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Hexosaminidase A anticorps

Épitope: C-Term

Fonction: HEXA Antibody - C-terminal region

Séquence: WKDFYIVEPL AFEGTPEQKA LVIGGEACMW GEYVDNTNLV PRLWPRAGAV

Homologie: Cow: 93%, Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HEXA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HEXA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61100-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Hexosaminidase A

Antigène: Hexosaminidase A (HEXA)

Autre désignation: HEXA

Sujet:

Targeted Subunit: alpha

Background Information: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

Gene Name: Hexosaminidase A (alpha polypeptide)

Alternative Symbols: TSD

Protein Name: Beta-hexosaminidase subunit alpha

Poids moléculaire: 61 kDa

ID gène: 3073

NCBI Accession: NP_000511

UniProt: P06865

Pathways: Sensory Perception of Sound, Glycosaminoglycan Metabolic Process