Hexosaminidase A anticorps (C-Term)

N° du produit ABIN2788673

Détail du produit anti-Hexosaminidase A anticorps

Antigène: Hexosaminidase A (HEXA)

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Porc, Boeuf (Vache), Cheval, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hexosaminidase A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: WKDFYIVEPL AFEGTPEQKA LVIGGEACMW GEYVDNTNLV PRLWPRAGAV

Homologie: Cow: 93%, Dog: 85%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HEXA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HEXA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 529 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Hexosaminidase A

Antigène: Hexosaminidase A (HEXA)

Autre désignation: HEXA (HEXA Produits)

Synonymes: anticorps TSD, anticorps fc04h11, anticorps wu:fc04h11, anticorps wu:fv09f06, anticorps si:dkey-35i22.2, anticorps HEXA, anticorps Hex-1, anticorps zgc:112084, anticorps hexosaminidase subunit alpha, anticorps hexosaminidase B (beta polypeptide), anticorps CUGBP Elav-like family member 6, anticorps hexosaminidase A, anticorps hexosaminidase A (alpha polypeptide), anticorps beta-hexosaminidase subunit alpha-like, anticorps HEXA, anticorps hexb, anticorps CELF6, anticorps Hexa, anticorps hexa, anticorps LOC100228061

Sujet: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Alias Symbols: MGC99608, TSD
Protein Interaction Partner: H2AFV, WDR61, UBA6, UBR7, C9orf78, HERC4, FKBP9, PDCD10, NUBP2, GTF3C4, HIST1H2BO, XPNPEP1, EZR, RAD23A, PCNA, KTN1, HK1, GDI1, CAPZB, AHCY, ACAT2, FBXO6, H2AFX, GM2A, USP22,
Protein Size: 529

Poids moléculaire: 48 kDa

ID gène: 3073

NCBI Accession: NM_000520, NP_000511

UniProt: P06865

Pathways: Sensory Perception of Sound, Glycosaminoglycan Metabolic Process