GABBR2 anticorps (C-Term)

N° du produit ABIN2788680

Détail du produit anti-GABBR2 anticorps

Antigène: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABBR2 est non-conjugé

Application: Western Blotting (WB)

Séquence: QFTQNQKKED SKTSTSVTSV NQASTSRLEG LQSENHRLRM KITELDKDLE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GABBR2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human GABBR2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 941 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GABBR2

Antigène: GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))

Autre désignation: GABBR2 (GABBR2 Produits)

Synonymes: anticorps Gpr51, anticorps GABABR2, anticorps GPR51, anticorps GPRC3B, anticorps HG20, anticorps HRIHFB2099, anticorps Gb2, anticorps Gm425, anticorps GABA(B)R2, anticorps si:dkey-190l1.2, anticorps gamma-aminobutyric acid type B receptor subunit 2, anticorps gamma-aminobutyric acid (GABA) B receptor, 2, anticorps gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog, anticorps GABBR2, anticorps LOC100448699, anticorps gabbr2, anticorps Gabbr2, anticorps gabbr2.S

Sujet: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Alias Symbols: FLJ36928, GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099
Protein Interaction Partner: KCTD12, GLP1R, Dlg4, GRASP, ATF4, ATF5, GABBR1, SH3GL3, NSF, HTR1A,
Protein Size: 941

Poids moléculaire: 106 kDa

ID gène: 9568

NCBI Accession: NM_005458, NP_005449

UniProt: O75899

Pathways: cAMP Metabolic Process