GABBR2 anticorps (C-Term)
Aperçu rapide pour GABBR2 anticorps (C-Term) (ABIN2788680)
Antigène
Voir toutes GABBR2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Fonction
- GABBR2 Antibody - C-terminal region
-
Séquence
- QFTQNQKKED SKTSTSVTSV NQASTSRLEG LQSENHRLRM KITELDKDLE
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
-
Attributs du produit
- This is a rabbit polyclonal antibody against GABBR2. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human GABBR2
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61115-100UG
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- prevent freeze-thaw cycles
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
-
Autre désignation
- GABBR2
-
Sujet
-
Targeted Subunit: 2
Background Information: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Gene Name: Gamma-aminobutyric acid (GABA) B receptor, 2
Alternative Symbols: HG20, DEE59, GPR51, EIEE59, GPRC3B, NDPLHS, GABABR2, HRIHFB2099
Protein Name: Gamma-aminobutyric acid type B receptor subunit 2
-
Poids moléculaire
- 106kDa
-
ID gène
- 9568
-
NCBI Accession
- NP_005449
-
UniProt
- O75899
-
Pathways
- cAMP Metabolic Process
Antigène
-