PFKM anticorps (C-Term)

N° du produit ABIN2788704

Cet anticorps Lapin Polyclonal détecte spécifiquement PFKM dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio) et Boeuf (Vache).

Aperçu rapide pour PFKM anticorps (C-Term) (ABIN2788704)

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PFKM anticorps

Épitope: C-Term

Fonction: PFKM Antibody - C-terminal region

Séquence: RALVFQPVAE LKDQTDFEHR IPKEQWWLKL RPILKILAKY EIDLDTSDHA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PFKM. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PFKM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61167-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PFKM

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Autre désignation: PFKM

Sujet:

Background Information: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

Gene Name: Phosphofructokinase, muscle

Alternative Symbols: GSD7, PFK1, PFKA, PFKX, PFK-1, PFK-A, ATP-PFK, PPP1R122

Protein Name: 6-phosphofructokinase, muscle type

Poids moléculaire: 85kDa

ID gène: 5213

NCBI Accession: NP_000280

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg