UNG anticorps (C-Term)
Aperçu rapide pour UNG anticorps (C-Term) (ABIN2788718)
Antigène
Voir toutes UNG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- UNG Antibody - C-terminal region
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Séquence
- GWAKQGVLLL NAVLTVRAHQ ANSHKERGWE QFTDAVVSWL NQNSNGLVFL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%, Yeast: 79%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against UNG. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61205-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- UNG (Uracil-DNA Glycosylase (UNG))
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Autre désignation
- UNG
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Sujet
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Background Information: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Gene Name: Uracil-DNA glycosylase
Alternative Symbols: DGU, UDG, UNG1, UNG2, HIGM4, HIGM5, UNG15
Protein Name: Uracil-DNA glycosylase
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Poids moléculaire
- 34kDa
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ID gène
- 7374
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NCBI Accession
- NP_550433
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UniProt
- P13051
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Pathways
- Réparation de l'ADN, Production of Molecular Mediator of Immune Response
Antigène
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