XPA anticorps (C-Term)
Aperçu rapide pour XPA anticorps (C-Term) (ABIN2788719)
Antigène
Voir toutes XPA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- MKQKKFDKKV KELRRAVRSS VWKRETIVHQ HEYGPEENLE DDMYRKTCTM
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Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against XPA. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 273 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
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Autre désignation
- XPA
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Sujet
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This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: XP1, XPAC
Protein Interaction Partner: NDEL1, TRIM27, HERC2, ATR, PRKDC, ATM, HMGB1, ERCC1, DDB2, DDB1, RPA1, XPC, POLR2A, HHV8GK18_gp81, GTF2H1, ERCC6, RPA2, MSH3, MSH2, XAB2, GPN1, RPA4, RASSF1, GTF2E2, EP300,
Protein Size: 273 -
Poids moléculaire
- 31 kDa
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ID gène
- 7507
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NCBI Accession
- NM_000380, NP_000371
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UniProt
- P23025
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Pathways
- Réparation de l'ADN
Antigène
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