XPA anticorps (C-Term)

N° du produit ABIN2788719

Détail du produit anti-XPA anticorps

Antigène: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XPA est non-conjugé

Application: Western Blotting (WB)

Séquence: MKQKKFDKKV KELRRAVRSS VWKRETIVHQ HEYGPEENLE DDMYRKTCTM

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against XPA. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 273 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur XPA

Antigène: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Autre désignation: XPA (XPA Produits)

Synonymes: anticorps CG6358, anticorps DhR14, anticorps DhXPA, anticorps DmXPA, anticorps Dmel\\CG6358, anticorps Dxpa, anticorps EG:EG0007.8, anticorps XPAC, anticorps XPA_DROME, anticorps Xpa, anticorps dmXPA, anticorps dxpa, anticorps XP1, anticorps AI573865, anticorps Xpac, anticorps xpac, anticorps xxpa, anticorps Xeroderma pigmentosum group A-like, anticorps XPA, DNA damage recognition and repair factor, anticorps xeroderma pigmentosum, complementation group A, anticorps xeroderma pigmentosum, complementation group A L homeolog, anticorps Xpac, anticorps XPA, anticorps Xpa, anticorps xpa.L

Sujet: This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: XP1, XPAC
Protein Interaction Partner: NDEL1, TRIM27, HERC2, ATR, PRKDC, ATM, HMGB1, ERCC1, DDB2, DDB1, RPA1, XPC, POLR2A, HHV8GK18_gp81, GTF2H1, ERCC6, RPA2, MSH3, MSH2, XAB2, GPN1, RPA4, RASSF1, GTF2E2, EP300,
Protein Size: 273

Poids moléculaire: 31 kDa

ID gène: 7507

NCBI Accession: NM_000380, NP_000371

UniProt: P23025

Pathways: Réparation de l'ADN