RCC1 anticorps (C-Term)
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- Antigène Voir toutes RCC1 Anticorps
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RCC1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- AWGMGTNYQL GTGQDEDAWS PVEMMGKQLE NRVVLSVSSG GQHTVLLVKD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against RCC1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product RCC1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 421 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
- Autre désignation
- RCC1 (RCC1 Produits)
- Synonymes
- anticorps Chc1, anticorps zgc:65796, anticorps zgc:77114, anticorps wu:fj77f08, anticorps rcc1, anticorps chc1-a, anticorps BJ1, anticorps CG10480, anticorps CG18640 (Bj1), anticorps Dmel\\CG10480, anticorps RCC1, anticorps RanGEF, anticorps Rcc1, anticorps dRCC1, anticorps inxs, anticorps sdt, anticorps xrcc1, anticorps chc1-b, anticorps MGC115703, anticorps MGC132085, anticorps CHC1, anticorps RCC1-I, anticorps SNHG3-RCC1, anticorps 4931417M11Rik, anticorps AI326872, anticorps regulator of chromosome condensation 1, anticorps regulator of chromosome condensation 1 L homeolog, anticorps Regulator of chromosome condensation 1, anticorps N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted, anticorps regulator of chromosome condensation 1 S homeolog, anticorps rcc1, anticorps RCC1, anticorps rcc1.L, anticorps Rcc1, anticorps rcc1.S
- Sujet
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RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Alias Symbols: CHC1, RCC1-I, SNHG3-RCC1
Protein Interaction Partner: UBC, SUMO2, SUMO1, NEDD8, MDM2, SUZ12, RNF2, PTMA, HDAC9, HMGA1, VCAM1, ITGA4, FN1, U2AF1, RANBP1, RAN, HNRNPM, HNRNPK, LUC7L3, SF3B6, NCSTN, ACIN1, RBM14, HDGF, SPRED1, FLAD1, WIZ, LRIF1, CSAD, SDF4, TRMT2A, DDAH2, FAF1, NUDT21, CCT7, TUBB3, CDK2AP2, KMT
Protein Size: 421 - Poids moléculaire
- 45 kDa
- ID gène
- 1104
- NCBI Accession
- NM_001269, NP_001260
- UniProt
- P18754
- Pathways
- Chromatin Binding, Protein targeting to Nucleus
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