EIF6 anticorps (C-Term)
Aperçu rapide pour EIF6 anticorps (C-Term) (ABIN2788786)
Antigène
Voir toutes EIF6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- QVLVGSYCVF SNQGGLVHPK TSIEDQDELS SLLQVPLVAG TVNRGSEVIA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against EIF6. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 245 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
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Autre désignation
- EIF6
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Sujet
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Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits.
Alias Symbols: 2, CAB, EIF3A, ITGB4BP, b, b(2)gcn, gcn, p27BBP, eIF-6, p27(BBP)
Protein Interaction Partner: ZNF622, BCCIP, PPAN, NMD3, GLTSCR2, GTPBP4, POP1, TOP2B, TOP2A, RNF2, CNBP, RARS, PPP5C, PEPD, PAFAH1B2, HSPA9, HSPA1A, HPRT1, EIF4E, DFFA, CFL1, CAPN1, ASNA1, GINS3, BZW2, ABHD14A, TNFAIP8, XRN2, HDAC9, ZBTB26, VCAM1, UBC, ECT2, HNRNPU, FBL, DHX9, APP, R
Protein Size: 245 -
Poids moléculaire
- 27 kDa
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ID gène
- 3692
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NCBI Accession
- NM_002212, NP_002203
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UniProt
- P56537
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Antigène
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