SCARB2 anticorps (C-Term)

N° du produit ABIN2788868

Détail du produit anti-SCARB2 anticorps

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB2 est non-conjugé

Application: Western Blotting (WB)

Séquence: KSMINTTLII TNIPYIIMAL GVFFGLVFTW LACKGQGSMD EGTADERAPL

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against SCARB2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCARB2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SCARB2

Antigène: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Autre désignation: SCARB2 (SCARB2 Produits)

Synonymes: anticorps cd36l2, anticorps fi13c07, anticorps chunp6914, anticorps wu:fi13c07, anticorps SCARB2, anticorps scarb2, anticorps AMRF, anticorps CD36L2, anticorps EPM4, anticorps HLGP85, anticorps LGP85, anticorps LIMP-2, anticorps LIMPII, anticorps SR-BII, anticorps 9330185J12Rik, anticorps Cd36l2, anticorps MLGP85, anticorps LimpII, anticorps scavenger receptor class B, member 2a, anticorps scavenger receptor class B member 2, anticorps scavenger receptor class B, member 2, anticorps scarb2a, anticorps SCARB2, anticorps scarb2, anticorps Scarb2

Sujet: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF).
Alias Symbols: AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII
Protein Interaction Partner: UBC, ATP4A, TAF15, NONO, HSPD1, DDX1, ATP6V1B1, Ap1g1, AP3S2, AP3S1, THBS1,
Protein Size: 478

Poids moléculaire: 50 kDa

ID gène: 950

NCBI Accession: NM_005506, NP_005497

UniProt: Q14108