UBE2V1 anticorps (C-Term)
Aperçu rapide pour UBE2V1 anticorps (C-Term) (ABIN2788878)
Antigène
Voir toutes UBE2V1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- GVVDPRAISV LAKWQNSYSI KVVLQELRRL MMSKENMKLP QPPEGQCYSN
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against UBE2V1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 147 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
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Autre désignation
- UBE2V1
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Sujet
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Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
Protein Interaction Partner: UBC, TRAF6, ube2nb, UBQLN1, FAM168A, TRAF3IP2, STUB1, PARK2, TXNDC5, YWHAQ, ECHS1, YWHAZ, YWHAG, TGM2, LDHB, SFN, G6PD, IQCB1, PELI3, ULK4, POMP, UBXN7, UBE2C, AHCYL1, SSSCA1, UBE4B, TTC9C, ATP6V1G1, ATP6V1F, ZYX, UGDH, UCHL3, UBE2V2, UBE2N, UBE2D2, UBE2B
Protein Size: 147 -
Poids moléculaire
- 16 kDa
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ID gène
- 7335
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NCBI Accession
- NM_001032288, NP_001027459
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UniProt
- Q13404
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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