UBE2V1 anticorps (N-Term)

N° du produit ABIN2788879

L’anticorps Lapin Polyclonal anti-UBE2V1 a été validé pour WB. Il convient pour détecter UBE2V1 dans des échantillons de Humain.

Aperçu rapide pour UBE2V1 anticorps (N-Term) (ABIN2788879)

Antigène: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2V1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBE2V1 anticorps

Épitope: N-Term

Séquence: GEVQASYLKS QSKLSDEGRL EPRKFHCKGV KVPRNFRLLE ELEEGQKGVG

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2V1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 170 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBE2V1

Antigène: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Autre désignation: UBE2V1

Sujet: Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
Protein Interaction Partner: UBC, TRAF6, ube2nb, UBQLN1, FAM168A, TRAF3IP2, STUB1, PARK2, TXNDC5, YWHAQ, ECHS1, YWHAZ, YWHAG, TGM2, LDHB, SFN, G6PD, IQCB1, PELI3, ULK4, POMP, UBXN7, UBE2C, AHCYL1, SSSCA1, UBE4B, TTC9C, ATP6V1G1, ATP6V1F, ZYX, UGDH, UCHL3, UBE2V2, UBE2N, UBE2D2, UBE2B
Protein Size: 170

Poids moléculaire: 19 kDa

ID gène: 7335

NCBI Accession: NM_021988, NP_068823

UniProt: Q13404

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades