PDGFC anticorps (N-Term)

N° du produit ABIN2788903

Détail du produit anti-PDGFC anticorps

Antigène: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDGFC est non-conjugé

Application: Western Blotting (WB)

Séquence: MLLLGLLLLT SALAGQRTGT RAESNLSSKL QLSSDKEQNG VQDPRHERVV

Homologie: Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against Pdgfc. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Pdgfc

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDGFC

Antigène: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Autre désignation: Pdgfc (PDGFC Produits)

Synonymes: anticorps SCDGF, anticorps FALLOTEIN, anticorps 1110064L01Rik, anticorps AI647969, anticorps PDGF-C, anticorps platelet derived growth factor C, anticorps platelet-derived growth factor, C polypeptide, anticorps PDGFC, anticorps Pdgfc

Classe de substances: Viral Protein

Sujet: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.
Alias Symbols: 1110064L01Rik, AI647969, PDGF-C
Protein Size: 345

Poids moléculaire: 39 kDa

ID gène: 54635

NCBI Accession: NM_019971, NP_064355

UniProt: Q8CI19

Pathways: Signalisation RTK, Platelet-derived growth Factor Receptor Signaling