PFKFB1 anticorps (C-Term)
Aperçu rapide pour PFKFB1 anticorps (C-Term) (ABIN2788933)
Antigène
Voir toutes PFKFB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- PFKFB1 Antibody - C-terminal region
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Séquence
- CPLHTVLKLT PVAYGCKVES IYLNVEAVNT HREKPENVDI TREPEEALDT
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against PFKFB1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61878-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
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Autre désignation
- PFKFB1
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Sujet
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Background Information: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Alternative Symbols: F6PK, HL2K, PFRX
Protein Name: 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1 EMBL AAH96078.1
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Poids moléculaire
- 52kDa
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ID gène
- 5207
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NCBI Accession
- NP_002616
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UniProt
- Q4VBA8
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Pathways
- Regulation of Carbohydrate Metabolic Process
Antigène
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