HMGN3 anticorps (Middle Region)

N° du produit ABIN2788959

Détail du produit anti-HMGN3 anticorps

Antigène: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cheval, Chien, Cobaye, Lapin, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGN3 est non-conjugé

Application: Western Blotting (WB)

Séquence: SKPRKTSAKK EPGTKISRGA KGKKEEKQEA GEEGTAPSAN GDTKVEEAQR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Hmgn3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Mouse Hmgn3

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HMGN3

Antigène: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Autre désignation: Hmgn3 (HMGN3 Produits)

Synonymes: anticorps Trip7, anticorps PNAS-25, anticorps TRIP7, anticorps 1110002A15Rik, anticorps 6330514M13Rik, anticorps BB071015, anticorps high mobility group nucleosomal binding domain 3 L homeolog, anticorps high mobility group nucleosomal binding domain 3, anticorps hmgn3.L, anticorps HMGN3, anticorps Hmgn3

Sujet: Hmgn3 binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. It affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion, regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors and regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. It may play a role in ocular development and astrocyte function.
Alias Symbols: 1110002A15Rik, 6330514M13Rik, BB071015, TRIP7
Protein Size: 99

Poids moléculaire: 11 kDa

ID gène: 94353

NCBI Accession: NM_026122, NP_080398

UniProt: Q9DCB1