This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This HMGN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN3.
anticorps Trip7, anticorps PNAS-25, anticorps TRIP7, anticorps 1110002A15Rik, anticorps 6330514M13Rik, anticorps BB071015, anticorps high mobility group nucleosomal binding domain 3 L homeolog, anticorps high mobility group nucleosomal binding domain 3, anticorps hmgn3.L, anticorps HMGN3, anticorps Hmgn3
Sujet
Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Two transcript variants encoding different isoforms have been found for this gene.