BAG5 anticorps (C-Term)

N° du produit ABIN2788981

Cité dans 1 publication. Cet anticorps anti-BAG5 Polyclonal Lapin (ABIN2788981) détecte spécifiquement BAG5 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye et Porc.

Aperçu rapide pour BAG5 anticorps (C-Term) (ABIN2788981)

Antigène: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BAG5 anticorps

Épitope: C-Term

Fonction: BAG5 Antibody - C-terminal region

Séquence: LEKRKLFACE EHPSHKAVWN VLGNLSEIQG EVLSFDGNRT DKNYIRLEEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against BAG5. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61996-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-BAG5 (ABIN2788981)

Yue, Zhao, Huang, Li, Zhu, Feng, Hu: "A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis." dans: Cell discovery, Vol. 2, pp. 16039, (2016) (PubMed).

Détails sur BAG5

Antigène: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Autre désignation: BAG5

Sujet:

Background Information: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.

Gene Name: BCL2-associated athanogene 5

Alternative Symbols: BAG-5

Protein Name: BAG family molecular chaperone regulator 5

Poids moléculaire: 56kDa

ID gène: 9529

NCBI Accession: NP_001015049

UniProt: Q9UL15

Pathways: SARS-CoV-2 Protein Interactome