KIF7 anticorps (C-Term)

N° du produit ABIN2490336

Détail du produit anti-KIF7 anticorps

Antigène: KIF7 (Kinesin Family Member 7 (KIF7))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF7 est non-conjugé

Application: Western Blotting (WB)

Séquence: RDLVHAPLPL TWKRSSLCGE EQGSPEELRQ REAAEPLVGR VLPVGEAGLP

Homologie: Cow: 92%, Dog: 79%, Human: 100%, Mouse: 77%, Pig: 100%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against KIF7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human KIF7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KIF7

Antigène: KIF7 (Kinesin Family Member 7 (KIF7))

Autre désignation: KIF7 (KIF7 Produits)

Synonymes: anticorps KIF7, anticorps DDBDRAFT_0204609, anticorps DDBDRAFT_0206583, anticorps DDB_0204609, anticorps DDB_0206583, anticorps ACLS, anticorps HLS2, anticorps JBTS12, anticorps UNQ340, anticorps cos2, anticorps costal2, anticorps kinesin family member 7, anticorps KIF7, anticorps kif7, anticorps Kif7

Sujet: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Alias Symbols: ACLS, AGBK, HLS2, JBTS12, UNQ340
Protein Size: 829

Poids moléculaire: 91 kDa

ID gène: 374654

NCBI Accession: NM_198525, NP_940927

UniProt: Q2M1P5

Pathways: Signalisation Hedgehog