RASAL1 anticorps (C-Term)
Aperçu rapide pour RASAL1 anticorps (C-Term) (ABIN2789073)
Antigène
Voir toutes RASAL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- RASAL1 Antibody - C-terminal region
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Séquence
- DTTLEADTGA CPEVLARQRA ATARLLEVLA DLDRAHEEFQ QQERGKAALG
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Homologie
- Human: 100%, Pig: 83%
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Attributs du produit
- This is a rabbit polyclonal antibody against RASAL1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62227-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
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Autre désignation
- RASAL1
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Sujet
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Background Information: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
Gene Name: RAS protein activator like 1 (GAP1 like)
Alternative Symbols: RASAL
Protein Name: RasGAP-activating-like protein 1
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Poids moléculaire
- 88kDa
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ID gène
- 8437
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NCBI Accession
- NP_004649
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UniProt
- O95294
Antigène
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