DRD3 anticorps (C-Term)

N° du produit ABIN2789395

L’anticorps Lapin Polyclonal anti-DRD3 a été validé pour WB. Il convient pour détecter DRD3 dans des échantillons de Humain, Rat, Chien, Cheval, Porc, Boeuf (Vache) et Cobaye.

Aperçu rapide pour DRD3 anticorps (C-Term) (ABIN2789395)

Antigène: DRD3 (Dopamine Receptor D3 (DRD3))

Reactivité: Humain, Rat, Chien, Cheval, Porc, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DRD3 anticorps

Épitope: C-Term

Séquence: QERGGELKRE EKTRNSLMPL REKKATQMVA IVLGAFIVCW LPFFLTHVLN

Homologie: Cow: 77%, Dog: 86%, Guinea Pig: 75%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DRD3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 367 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DRD3

Antigène: DRD3 (Dopamine Receptor D3 (DRD3))

Autre désignation: DRD3

Sujet: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Alias Symbols: D3DR, ETM1, FET1, MGC149204, MGC149205
Protein Interaction Partner: SLC9A3, USP48, EEF1G, CLIC6, MPDZ, EPB41L2, GIPC1, NCS1, EPB41L1, EEF1B2, NCK1, FLNA, GNAI1, EPB41, GRB2, RDX,
Protein Size: 367

Poids moléculaire: 41 kDa

ID gène: 1814

NCBI Accession: NM_033663, NP_387512

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity