MCAM anticorps (Middle Region)

N° du produit ABIN2789518

Cet anticorps Lapin Polyclonal détecte spécifiquement MCAM dans WB. Il présente une réactivité avec des échantillons de Humain, Lapin, Porc, Cheval et Boeuf (Vache).

Aperçu rapide pour MCAM anticorps (Middle Region) (ABIN2789518)

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reactivité: Humain, Lapin, Porc, Cheval, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCAM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MCAM anticorps

Épitope: Middle Region

Fonction: MCAM Antibody - middle region

Séquence: PSTREAEEET TNDNGVLVLE PARKEHSGRY ECQGLDLDTM ISLLSEPQEL

Homologie: Cow: 86%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against MCAM. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63483-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MCAM

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation: MCAM

Sujet:

Background Information: MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. MCAM could be an adhesion molecule active in neural crest cells during embryonic development. MCAM acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Gene Name: Melanoma cell adhesion molecule

Alternative Symbols: CD146, MUC18, HEMCAM, METCAM, MelCAM

Protein Name: Cell surface glycoprotein MUC18

Poids moléculaire: 71kDa

ID gène: 4162

NCBI Accession: NP_006491

UniProt: P43121