Sclerostin anticorps (N-Term)

N° du produit ABIN2789538

Cet anticorps Lapin Polyclonal détecte spécifiquement Sclerostin dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Cheval, Porc, Boeuf (Vache), Cobaye et Lapin.

Aperçu rapide pour Sclerostin anticorps (N-Term) (ABIN2789538)

Antigène: Sclerostin (SOST)

Reactivité: Humain, Souris, Rat, Chien, Cheval, Porc, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sclerostin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Sclerostin anticorps

Épitope: N-Term

Fonction: SOST Antibody - N-terminal region

Séquence: PELGEYPEPP PELENNKTMN RAENGGRPPH HPFETKDVSE YSCRELHFTR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SOST. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63544-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Sclerostin

Antigène: Sclerostin (SOST)

Autre désignation: SOST

Sujet:

Background Information: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Gene Name: Sclerostin

Alternative Symbols: CDD, VBCH, DAND6, SOST1

Protein Name: Sclerostin

Poids moléculaire: 23kDa

ID gène: 50964

NCBI Accession: NP_079513

UniProt: Q9BQB4