IL5RA anticorps (N-Term)

N° du produit ABIN2789551

L’anticorps Lapin Polyclonal anti-IL5RA a été validé pour WB. Il convient pour détecter IL5RA dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc et Saccharomyces cerevisiae.

Aperçu rapide pour IL5RA anticorps (N-Term) (ABIN2789551)

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL5RA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL5RA anticorps

Épitope: N-Term

Séquence: GLAQVLLQWK PNPDQEQRNV NLEYQVKINA PKEDDYETRI TESKCVTILH

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 79%, Yeast: 91%

Attributs du produit: This is a rabbit polyclonal antibody against IL5RA. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 420 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL5RA

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Autre désignation: IL5RA

Sujet: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Alias Symbols: CD125, CDw125, HSIL5R3, IL5R, MGC26560
Protein Interaction Partner: UNC119, SDCBP, IL5, JAK2, JAK1, CSF2RB,
Protein Size: 420

Poids moléculaire: 46 kDa

ID gène: 3568

NCBI Accession: NM_175726, NP_783853

UniProt: Q01344

Pathways: Signalistation JAK/STAT