IDUA anticorps (C-Term)

N° du produit ABIN2789573

Cet anticorps Lapin Polyclonal détecte spécifiquement IDUA dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval et Chien.

Aperçu rapide pour IDUA anticorps (C-Term) (ABIN2789573)

Antigène: IDUA (Iduronidase, alpha-L- (IDUA))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDUA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IDUA anticorps

Épitope: C-Term

Fonction: IDUA Antibody - C-terminal region

Séquence: DPVAAAPRPL PAGGRLTLRP ALRLPSLLLV HVCARPEKPP GQVTRLRALP

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 80%

Attributs du produit: This is a rabbit polyclonal antibody against IDUA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IDUA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63635-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IDUA

Antigène: IDUA (Iduronidase, alpha-L- (IDUA))

Autre désignation: IDUA

Sujet:

Background Information: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

Gene Name: iduronidase, alpha-L-

Alternative Symbols: IDA, MPS1, MPSI

Protein Name: Alpha-L-iduronidase

Poids moléculaire: 73 kDa

ID gène: 3425

UniProt: P35475

Pathways: Glycosaminoglycan Metabolic Process