GCKR anticorps (C-Term)

N° du produit ABIN2789592

Cet anticorps Lapin Polyclonal détecte spécifiquement GCKR dans WB. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour GCKR anticorps (C-Term) (ABIN2789592)

Antigène: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCKR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GCKR anticorps

Épitope: C-Term

Séquence: PIALLSLLFR CSITEAQAHL AAAPSVCEAV RSALAGPGQK RTADPLEILE

Homologie: Human: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against GCKR. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 625 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GCKR

Antigène: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Autre désignation: GCKR

Sujet: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
Alias Symbols: GKRP, FGQTL5
Protein Interaction Partner: CDKN1A, UBC, TRAF2, GCK,
Protein Size: 625

Poids moléculaire: 68 kDa

ID gène: 2646

NCBI Accession: NM_001486, NP_001477

UniProt: Q14397

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus