SCG5 anticorps (C-Term)

N° du produit ABIN2789642

Détail du produit anti-SCG5 anticorps

Antigène: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCG5 est non-conjugé

Application: Western Blotting (WB)

Séquence: QHLFDPEHDY PGLGKWNKKL LYEKMKGGER RKRRSVNPYL QGQRLDNVVA

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SCG5. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 212 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SCG5

Antigène: SCG5 (Secretogranin V (7B2 Protein) (SCG5))

Autre désignation: SCG5 (SCG5 Produits)

Synonymes: anticorps zgc:73132, anticorps sgne1, anticorps MGC145087, anticorps 7B2, anticorps AI325031, anticorps Sgne-1, anticorps Sgne1, anticorps P7B2, anticorps SGNE1, anticorps SgV, anticorps secretogranin V, anticorps scg5, anticorps SCG5, anticorps Scg5

Sujet: SCG5 acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. SCG5 binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. SCG5 is also required for cleavage of PCSK2 but does not appear to be involved in its folding. SCG5 plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
Alias Symbols: 7B2, P7B2, SGNE1, SgV
Protein Interaction Partner: UBQLN1, KHDRBS1, UBQLN4, NR1H2, PCSK2,
Protein Size: 212

Poids moléculaire: 23 kDa

ID gène: 6447

NCBI Accession: NM_001144757, NP_001138229

UniProt: P05408