MCPH1 anticorps (C-Term)

N° du produit ABIN2789647

Détail du produit anti-MCPH1 anticorps

Antigène: MCPH1 (Microcephalin 1 (MCPH1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCPH1 est non-conjugé

Application: Western Blotting (WB)

Séquence: VLDDSCDGFK DLIKPHEELK KSGRGKKPTR TLVMTSMPSE KQNVVIQVVD

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MCPH1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 835 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MCPH1

Antigène: MCPH1 (Microcephalin 1 (MCPH1))

Autre désignation: MCPH1 (MCPH1 Produits)

Synonymes: anticorps RGD1560642, anticorps MGC83773, anticorps MCPH1, anticorps mct, anticorps brit1, anticorps MGC148665, anticorps BRIT1, anticorps MCT, anticorps 5430437K10Rik, anticorps D030046N04Rik, anticorps microcephalin 1, anticorps microcephalin 1 S homeolog, anticorps microcephaly, primary autosomal recessive 1, anticorps Mcph1, anticorps mcph1.S, anticorps MCPH1, anticorps mcph1

Sujet: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome.
Alias Symbols: BRIT1, FLJ12847, MCT
Protein Interaction Partner: KDM1A, PHF11, TADA2A, ABCC2, E2F1, CDC27, CHD4, H2AFX, CHEK1, MDC1, TP53BP1, SMARCC2, SMARCC1, SMARCB1, SMARCA4, SMARCA2, RAD51, NBN, MCM2, BRCA2, ATR, ATM, RPA1,
Protein Size: 835

Poids moléculaire: 93 kDa

ID gène: 79648

NCBI Accession: NM_024596, NP_078872

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance