GIPR anticorps (N-Term)
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- Antigène Voir toutes GIPR Anticorps
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GIPR est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GFVLRQCGSD GQWGLWRDHT QCENPEKNEA FLDQRLILER LQVMYTVGYS
- Homologie
- Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against GIPR. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product GIPR Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 466 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- Autre désignation
- GIPR (GIPR Produits)
- Synonymes
- anticorps GIPR, anticorps PGQTL2, anticorps GIP-R, anticorps Gm1081, anticorps Gm160, anticorps Gippr, anticorps RATGIPPR, anticorps gastric inhibitory polypeptide receptor, anticorps glucagon receptor, anticorps GIPR, anticorps LOC100303705, anticorps Gipr
- Sujet
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This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Alias Symbols: MGC126722, PGQTL2
Protein Interaction Partner: LNX1, UBC, GIP,
Protein Size: 466 - Poids moléculaire
- 53 kDa
- ID gène
- 2696
- NCBI Accession
- NM_000164, NP_000155
- UniProt
- P48546
- Pathways
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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