SHANK2 anticorps (C-Term)

N° du produit ABIN2789712

Détail du produit anti-SHANK2 anticorps

Antigène: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHANK2 est non-conjugé

Application: Western Blotting (WB)

Séquence: PQSPSLNSSQ PTNSADSKKP ASLSNCLPAS FLPPPESFDA VADSGIEEVD

Homologie: Cow: 100%, Dog: 85%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SHANK2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1254 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SHANK2

Antigène: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Autre désignation: SHANK2 (SHANK2 Produits)

Synonymes: anticorps AUTS17, anticorps CORTBP1, anticorps CTTNBP1, anticorps ProSAP1, anticorps SHANK, anticorps SPANK-3, anticorps mKIAA1022, anticorps auts17, anticorps cortbp1, anticorps cttnbp1, anticorps prosap1, anticorps spank-3, anticorps shank2, anticorps MGC122482, anticorps CortBP1, anticorps Spank-3, anticorps SHANK2, anticorps SH3 and multiple ankyrin repeat domains 2, anticorps SH3 and multiple ankyrin repeat domains 2 L homeolog, anticorps SH3 and multiple ankyrin repeat domains protein 2, anticorps SHANK2, anticorps Shank2, anticorps shank2.L, anticorps shank2, anticorps LOC100438523

Sujet: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain.
Alias Symbols: CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
Protein Interaction Partner: SHARPIN, NLK, LPHN1, DLGAP1, LPHN2, ARHGEF7, BAIAP2, DLG4, BAI2, DNM2, SSTR2, SLC9A3, CTTN, DLGAP3, DLGAP4, DLGAP2, DYNLL2, DYNLL1, MYO5A,
Protein Size: 1254

Poids moléculaire: 135 kDa

ID gène: 22941

NCBI Accession: NM_012309, NP_036441