DUSP4 anticorps (C-Term)

N° du produit ABIN2789728

L’anticorps anti-DUSP4 Polyclonal Lapin est utilisé pour la détection de DUSP4 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Porc. Il a été validé pour WB.

Aperçu rapide pour DUSP4 anticorps (C-Term) (ABIN2789728)

Antigène: DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DUSP4 anticorps

Épitope: C-Term

Fonction: DUSP4 Antibody - C-terminal region

Séquence: GQLLQFESQV LATSCAAEAA SPSGPLRERG KTPATPTSQF VFSFPVSVGV

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 85%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against DUSP4. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64085-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DUSP4

Antigène: DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))

Autre désignation: DUSP4

Sujet:

Background Information: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.

Gene Name: Dual specificity phosphatase 4

Alternative Symbols: TYP, HVH2, MKP2, MKP-2

Protein Name: Dual specificity protein phosphatase 4

Poids moléculaire: 43kDa

ID gène: 1846

NCBI Accession: NP_001385

UniProt: Q13115

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades