WISP2 anticorps (C-Term)

N° du produit ABIN2789751

L’anticorps anti-WISP2 Polyclonal Lapin est utilisé pour la détection de WISP2 dans des échantillons de Humain, Rat, Chien, Cheval et Porc. Il a été validé pour WB.

Aperçu rapide pour WISP2 anticorps (C-Term) (ABIN2789751)

Antigène: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Reactivité: Humain, Rat, Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WISP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-WISP2 anticorps

Épitope: C-Term

Fonction: WISP2 Antibody - C-terminal region

Séquence: WGPCSTTCGL GMATRVSNQN RFCRLETQRR LCLSRPCPPS RGRSPQNSAF

Homologie: Dog: 79%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against WISP2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64152-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur WISP2

Antigène: WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Autre désignation: WISP2

Sujet:

Background Information: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

Gene Name: WNT1 inducible signaling pathway protein 2

Alternative Symbols: CT58, WISP2, CTGF-L

Protein Name: WNT1-inducible-signaling pathway protein 2

Poids moléculaire: 24kDa

ID gène: 8839

NCBI Accession: NP_003872

UniProt: O76076

Pathways: Signalisation WNT, Growth Factor Binding