CDK2AP1 anticorps (C-Term)
Aperçu rapide pour CDK2AP1 anticorps (C-Term) (ABIN2789771)
Antigène
Voir toutes CDK2AP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- CDK2AP1 Antibody - C-terminal region
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Séquence
- LLAIIEELGK EIRPTYAGSK SAMERLKRGI IHARGLVREC LAETERNARS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against CDK2AP1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK2AP1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64230-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))
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Autre désignation
- CDK2AP1
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Sujet
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Background Information: The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Gene Name: Cyclin-dependent kinase 2 associated protein 1
Alternative Symbols: DOC1, ST19, DORC1, doc-1, p12DOC-1
Protein Name: Cyclin-dependent kinase 2-associated protein 1
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Poids moléculaire
- 12kDa
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ID gène
- 8099
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NCBI Accession
- NP_004633
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UniProt
- O14519
Antigène
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