TP53I3 anticorps (C-Term)
Aperçu rapide pour TP53I3 anticorps (C-Term) (ABIN2789865)
Antigène
Voir toutes TP53I3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- TP53I3 Antibody - C-terminal region
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Séquence
- SKLLFKRGSL ITSLLRSRDN KYKQMLVNAF TEQILPHFST EGPQRLLPVL
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Homologie
- Cow: 86%, Dog: 85%, Horse: 83%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against TP53I3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human TP53I3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64531-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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Autre désignation
- TP53I3
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Sujet
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Background Information: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.
Gene Name: Tumor protein p53 inducible protein 3
Alternative Symbols: PIG3
Protein Name: Tumor protein p53 inducible protein 3, isoform CRA_c EMBL EAX00765.1
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Poids moléculaire
- 26kDa
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ID gène
- 9540
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UniProt
- B4DMQ7
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Pathways
- Signalisation p53
Antigène
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