MMP25 anticorps (Middle Region)

N° du produit ABIN2789901

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP25 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cobaye, Cheval et Lapin.

Aperçu rapide pour MMP25 anticorps (Middle Region) (ABIN2789901)

Antigène: MMP25 (Matrix Metallopeptidase 25 (MMP25))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP25 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MMP25 anticorps

Épitope: Middle Region

Séquence: FGHALGLGHS SAPNSIMRPF YQGPVGDPDK YRLSQDDRDG LQQLYGKAPQ

Homologie: Dog: 82%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against MMP25. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 562 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MMP25

Antigène: MMP25 (Matrix Metallopeptidase 25 (MMP25))

Autre désignation: MMP25

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
Alias Symbols: MMP20, MMP20A, MMPL1, MT-MMP6, MT6-MMP
Protein Interaction Partner: CLU, MMP2,
Protein Size: 562

Poids moléculaire: 48 kDa

ID gène: 64386

NCBI Accession: NM_022468, NP_071913

UniProt: Q9NPA2