MMP25 anticorps (Middle Region)
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- Antigène Voir toutes MMP25 Anticorps
- MMP25 (Matrix Metallopeptidase 25 (MMP25))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MMP25 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- FGHALGLGHS SAPNSIMRPF YQGPVGDPDK YRLSQDDRDG LQQLYGKAPQ
- Homologie
- Dog: 82%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against MMP25. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product MMP25 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 562 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- MMP25 (Matrix Metallopeptidase 25 (MMP25))
- Autre désignation
- MMP25 (MMP25 Produits)
- Synonymes
- anticorps MMP-25, anticorps MMP20, anticorps MMP20A, anticorps MMPL1, anticorps MT-MMP 6, anticorps MT-MMP6, anticorps MT6-MMP, anticorps MT6MMP, anticorps MTMMP6, anticorps F730048C11Rik, anticorps Leukolysin, anticorps matrix metallopeptidase 25, anticorps MMP25, anticorps Mmp25
- Sujet
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
Alias Symbols: MMP20, MMP20A, MMPL1, MT-MMP6, MT6-MMP
Protein Interaction Partner: CLU, MMP2,
Protein Size: 562 - Poids moléculaire
- 48 kDa
- ID gène
- 64386
- NCBI Accession
- NM_022468, NP_071913
- UniProt
- Q9NPA2
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