IDO1 anticorps (C-Term)

N° du produit ABIN2789915

Cet anticorps anti-IDO1 est un anticorps Lapin Polyclonal détectant IDO1 dans WB. Adapté pour Humain, Porc et Lapin.

Aperçu rapide pour IDO1 anticorps (C-Term) (ABIN2789915)

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivité: Humain, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDO1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IDO1 anticorps

Épitope: C-Term

Séquence: ILIPASQQPK ENKTSEDPSK LEAKGTGGTD LMNFLKTVRS TTEKSLLKEG

Homologie: Human: 100%, Pig: 79%, Rabbit: 93%

Attributs du produit: This is a rabbit polyclonal antibody against IDO1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 403 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IDO1

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Autre désignation: IDO1

Sujet: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Alias Symbols: IDO, INDO, IDO-1
Protein Interaction Partner: UBC, APP, TERF2IP, PPP1R16A, DDX24,
Protein Size: 403

Poids moléculaire: 45 kDa

ID gène: 3620

NCBI Accession: NM_002164, NP_002155

UniProt: P14902

Pathways: Activated T Cell Proliferation