C8orf4 anticorps (N-Term)

N° du produit ABIN2790028

Détail du produit anti-C8orf4 anticorps

Antigène: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C8orf4 est non-conjugé

Application: Western Blotting (WB)

Séquence: TASRKKAVGN IFENTDQESL ERLFRNSGDK KAEERAKIIF AIDQDVEEKT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against C8orf4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human C8orf4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 106 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur C8orf4

Antigène: C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))

Autre désignation: C8orf4 (C8orf4 Produits)

Synonymes: anticorps TC-1, anticorps TC1, anticorps 1110065B09Rik, anticorps AW121743, anticorps AW321058, anticorps C8ORF4, anticorps transcriptional and immune response regulator, anticorps chromosome 22 open reading frame, human C8orf4, anticorps TCIM, anticorps C22H8ORF4, anticorps Tcim

Sujet: This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Alias Symbols: MGC22806, TC-1, TC1, hTC-1
Protein Interaction Partner: ELAVL1, UBC,
Protein Size: 106

Poids moléculaire: 12 kDa

ID gène: 56892

NCBI Accession: NM_020130, NP_064515

UniProt: Q9NR00