FKBP1A anticorps (N-Term)

N° du produit ABIN2790064

Cet anticorps anti-FKBP1A Polyclonal Lapin (ABIN2790064) détecte spécifiquement FKBP1A dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio).

Aperçu rapide pour FKBP1A anticorps (N-Term) (ABIN2790064)

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP1A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FKBP1A anticorps

Épitope: N-Term

Séquence: GQTCVVHYTG MLEDGKKFDS SRDRNKPFKF MLGKQEVIRG WEEGVAQMSV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against FKBP1A. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 108 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FKBP1A

Antigène: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Autre désignation: FKBP1A

Sujet: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Alias Symbols: FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PKCI2, PPIASE, FKBP-1A
Protein Interaction Partner: AHSP, SF3B4, MID1, MTOR, TGFB1, UBC, BAG3, ACVRL1, BARD1, ZPR1, APP, ELAVL1, ACVR1B, SMAD7, TRPC3, FKBP4, TGFB1I1, GLMN, PPP3R1, YY1, TGFBR1, FKBP1A, RYR3, RYR1, ITPR1, DHFR, PPP3CA, BMPR1A, RPTOR,
Protein Size: 108

Poids moléculaire: 12 kDa

ID gène: 2280

NCBI Accession: NM_000801, NP_000792

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process