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MYSM1 anticorps (C-Term)

MYSM1 Reactivité: Humain, Chien, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2790657
  • Antigène Voir toutes MYSM1 Anticorps
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    Épitope
    • 8
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    Humain, Chien, Lapin
    Hôte
    • 34
    Lapin
    Clonalité
    • 34
    Polyclonal
    Conjugué
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MYSM1 est non-conjugé
    Application
    • 21
    • 21
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    CLQKLLECMR KTLSKVTNCF MAEEFLTEIE NLFLSNYKSN QENGVTEENC
    Homologie
    Dog: 86%, Human: 100%, Rabbit: 77%
    Attributs du produit
    This is a rabbit polyclonal antibody against MYSM1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYSM1
    Top Product
    Discover our top product MYSM1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 828 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    Autre désignation
    MYSM1 (MYSM1 Produits)
    Synonymes
    anticorps 2A-DUB, anticorps 2ADUB, anticorps RP4-592A1.1, anticorps C130067A03Rik, anticorps C530050H10Rik, anticorps RGD1311787, anticorps 2adub, anticorps Myb like, SWIRM and MPN domains 1, anticorps myb-like, SWIRM and MPN domains 1, anticorps Myb like, SWIRM and MPN domains 1 L homeolog, anticorps MYSM1, anticorps Mysm1, anticorps mysm1.L
    Sujet
    MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. It preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
    Alias Symbols: 2A-DUB, 2ADUB, DKFZp779J1554, DKFZp779J1721, KIAA1915, RP4-592A1.1
    Protein Interaction Partner: UBC, DICER1, SUMO2, TUBB1, WDR77, STK38, PRMT5, KAT2B, HIST2H2AC, RBM10, KIF11, HSPA1A, HNRNPH1, EEF1A1,
    Protein Size: 828
    Poids moléculaire
    91 kDa
    ID gène
    114803
    NCBI Accession
    NM_001085487, NP_001078956
    UniProt
    Q5VVJ2
    Pathways
    Chromatin Binding
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